The infection of cervical intervertebral space is the rare Inflammatory disease of the cervical intervertebral disc, centrum and neighbouring vertebral endplate. This illness is liable to missed diagnosis and misdiagnosis on account of its insidious onset and scarce specificity in clinical symptoms. Distinguishingly, with the conditions being aggravated, the patients appear destructive neural functional defect in the early days. The occurrence rate of cervical vertebra is the lowest in pyogenic spondylitis, and the reports in regard to cervical intervertebral space''s Infection are rare relatively. A clinical research was reported about primary Infection of pyogenic cervical intervertebral space. And this review tried to summarize the research progress and Issues in the Infection of cervical intervertebral space in some ways.