Abstract:[Objective] To investigate the stress distribution characteristics of a new type of porous (metal) mesh cage and provide theoretical basis for clinical application. [Methods] Using a 3D printing technique, a new type of cervical porous (metal) mesh cage was developed. The traditional titanium mesh was used as a control to establish a three-dimensional limited use of anterior cervical corpectomy and fusion with two kinds of titanium mesh. In the model, a preload of 73.6 N was applied under the six conditions of flexion and extension, left and right flexion, left and right rotation, and the stress distribution of titanium mesh, titanium plate and end plate were observed and analyzed. [Results] Under six working conditions, compared with traditional titanium mesh, the maximal stress of the cervical porous (metal) mesh cage was reduced by 84%~98%, the largest stress on the end plate of C6 went down 29% ~ 83%, the greatest stress of the end plate under C4 was decreased by 8% ~ 55%. Under most working conditions, the maximum stress value of the titanium plate of the new cervical porous (metal) mesh cage is lower than that of the traditional titanium mesh cage, which reduced the stress shielding of the titanium plate, and combined the stress of the titanium plate and peak analysis of the displacement of the vertebral body, the novel cervical porous (metal) mesh cage had strong immediate stability. Under most conditions, the maximum endplate stress of the two titanium mesh cages was located at the trailing edge of the upper endplate, but the maximum stress value of the trailing edge of the endplate of the new cervical porous (metal) mesh cage was less than traditional titanium mesh, and there were significant differences. [Conclusion] Compared with the traditional titanium mesh cage, the new cervical porous (metal) mesh cage has strong immediate stability after anterior cervical corpectomy and fusion, and it can reduce stress concentration, stress shielding of the plate and the maximum stress of the upper and lower end plates. So it can better prevent the mesh cage from sinking.